Expresión de búsqueda: PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA 
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Descriptor Inglés:   Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha 
Descriptor Español:   Coactivador 1-alfa del Receptor Activado por Proliferadores de Peroxisomas gamma 
Descriptor Portugués:   Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo 
Sinónimos Inglés:   PGC 1 alpha Protein
PGC-1-alpha Protein
PPARGC 1 alpha Protein
PPARGC-1-alpha Protein
PPARGC1a Protein
Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 alpha  
Categoría:   D12.644.360.024.314.650
D12.776.157.057.080.650
D12.776.157.725.813.875
D12.776.476.024.394.650
D12.776.660.675.650
D12.776.664.962.813.875
D12.776.930.617.650
Definición Inglés:   A transcriptional co-activator for NUCLEAR RECEPTORS. It is characterized by an N-terminal LxxLL sequence, a region that interacts with PPAR GAMMA, and a C-terminal RNA RECOGNITION MOTIF. It increases expression of MITOCHONDRIAL UNCOUPLING PROTEIN to regulate genes involved in metabolic reprogramming in response to dietary restriction and the integration of CIRCADIAN RHYTHMS with ENERGY METABOLISM. 
Nota Histórica Inglés:   2017 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   56537 
Identificador Único:   D000071248 

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